Gout
Gout is a common, painful form of arthritis. It causes swollen, red, hot and stiff joints.Gout happens when uric acid builds up in your body. Uric acid comes from the breakdown of substances called purines. Purines are in your body's tissues and in foods, such as liver, dried beans and peas, and anchovies. Normally, uric acid dissolves in the blood. It passes through the kidneys and out of the body in urine. But sometimes uric acid can build up and form needle-like crystals. When they form in your joints, it is very painful. The crystals can also cause kidney stones.Often, gout first attacks your big toe. It can also attack ankles, heels, knees, wrists, fingers, and elbows. At first, gout attacks usually get better in days. Eventually, attacks last longer and happen more often.You are more likely to get gout if youAre a manHave family member with goutAre overweightDrink alcoholEat too many foods rich in purinesGout can be hard to diagnose. Your doctor may take a sample of fluid from an inflamed joint to look for crystals. You can treat gout with medicines.Pseudogout has similar symptoms and is sometimes confused with gout. However, it is caused by calcium phosphate, not uric acid.NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases
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Last week was back-to-back five bilobed bipaddled PMMC flaps for full-thickness buccal mucosa defects. It made me reflect— In India, where many patients present late with advanced head and neck cancers, and where microvascular expertise or resources may be limited, this flap becomes more than a salvage,It becomes a purposeful craft, especially when where risk, and resources are in short supply. Success in reconstruction lies less in patient factors, and more in the surgeon’s design and execution. Every wound dehiscence, infection, or flap failure often reflects a planning flaw rather than patient factors. The Bilobed PMMC Flap Is More Than a Procedure.It’s a mastery of balance between form and function & between art and science As surgical oncologists, we must reconstruct with the same precision we resect. Both are part of the same journey,and in that journey, mindful reconstruction is where true surgical wisdom lies. Here are my 2 cents for how to plan for Bilobed PMMC Flap ✅ Flap Design • Center on the Nipple-Areola Complex (NAC) • Inner paddle → inferolateral, for mucosal lining • Outer paddle → medial, for skin cover • Lateral “C” design allows a large harvest with primary closure ✅ Paddle Orientation • Taper both ends to prevent dog-ears • Leave 1 cm between paddles for de-epithelialization & tension-free folding ✅ Safe Flap Limits • Do not extend >2 cm beyond the pectoralis major borders to preserve viability ✅ Pedicle Handling • Avoid spiraling of the pedicle • If NAC is included, anticipate nipple positioning in inner paddle or mark inner paddle ✅ Commissure Reconstruction • Prioritize primary closure • Use flap bulk to maintain commissure symmetry and prevent deviation ✅ Nerve Division • Always divide the lateral pectoral nerve to prevent post-op compression Suggestions are welcome for insightful discussion regarding same .
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