Mantle cell lymphoma
An aggressive, usually diffuse non-Hodgkin lymphoma composed of small to medium sized B-lymphocytes (centrocytes). Most patients present with advanced stage disease with lymphadenopathy, hepatosplenomegaly, and bone marrow involvement. The gastrointestinal tract is the most commonly affected extranodal site by this type of non-Hodgkin lymphoma. The vast majority of cases express the t(11;14)(q13;q32) resulting in the rearrangement of the BCL-1 gene and the overexpression of cyclin D1 mRNA.
Disease Alternative Name
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Top doctors who continously share their opinions on Mantle cell lymphomaPacific Medical College
Assistant Professor
M.P.SHAH MEDICAL COLLEGE
M.D.

St John's Medical College
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Nizam's Institute of Medical Sciences
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